Catalog11 refs
Gonadorelin
ReproductivetherapeuticFertility & ReproductiveHormonalResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
Overview
Gonadorelin is a synthetic form of the naturally occurring gonadotropin-releasing hormone (GnRH). It stimulates the pituitary gland to release follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which in turn regulate testosterone production in men and ovulation in women. It is FDA-approved for diagnostic testing and fertility treatment. The pulsatile nature of GnRH secretion is critical for proper reproductive function.
Primary Uses
Fertility assessment
Treatment of low hormone levels
Maintaining testicular function during TRT
Stimulating ovulation in women
Stimulating spermatogenesis in men with hypothalamic hypogonadism
Preserving fertility and testicular size
Diagnostic evaluation of pituitary-gonadal function
Maintaining HPG axis function during testosterone-suppressing therapies
Preserving testicular function and fertility during TRT
Stimulating LH and FSH release via pulsatile administration
Gonadal hormone regulation
Fertility research
LH/FSH stimulation studies
GnRH receptor signaling
Stimulates natural testosterone production
Maintains testicular function during hormone therapy
Supports fertility in hypogonadal conditions
FDA-approved for diagnostic and therapeutic use
Can restore LH and FSH pulsatility
Alternative to hCG for testicular stimulation
Preserves endogenous hormone production
Hypogonadotropic Hypogonadism
Ovulation Induction
Male Fertility
Delayed Puberty
Pituitary Function Testing
LH/FSH Response Assessment
TRT Support
Post-Cycle Therapy
Cryptorchidism
Prostate cancer
Endometriosis
Precocious puberty
Testosterone support
Evaluating pituitary function
Inducing ovulation
Maintaining testicular size and fertility during TRT
Fertility induction
Protocol Reference
Dose
50–100 mcg per injection (pulsatile dosing)
Frequency
Pulsatile Pattern
Half-life
2–4 Minutes
Route
Subcutaneous · Intravenous
Evidence
Phase 4, FDA Approved / FDA-approved (Factrel) / Extensively Studied / FDA approved synthetic analogs / FDA Approved (disputed)
Research References· 3
Research Models
Human
Also in Reproductive