Catalog207 refs
LL-37 (Cathelicidin)
Immune ModulationResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
SkinCirculationJointsepithelial tissue
Overview
LL-37 is a natural human immune defense molecule (part of the cathelicidin family) that plays a key role in the body's first line of defense against infection. Research explores its antimicrobial, wound healing, and immune-regulating properties. It provides direct antimicrobial activity through membrane disruption while modulating immune responses and promoting wound healing.
Primary Uses
Antimicrobial activity against gram-positive bacteria, gram-negative bacteria, fungi, and enveloped viruses
Prevention and dispersion of bacterial biofilms for chronic infection treatment
Modulation of inflammatory responses via cytokine production
Recruitment of monocytes, neutrophils, T cells, and mast cells to infection sites
Promotion of wound healing through keratinocyte migration, angiogenesis, and epithelialization
Tissue repair and regeneration via effects on fibroblasts and endothelial cells
Protocol Reference
Dose
50–200 mcg
Frequency
1× daily
Route
Subcutaneous (SC) · Topical
Evidence
Phase 2
Research Models
Human
Also in Immune Modulation