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LL-37 (Human Cathelicidin)

Immune ModulationResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Short (rapid proteolytic degradation)
Half-life
10
Uses
0.5-1.6 mg
Typical
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SkinCirculationJointsepithelial tissue
Overview

LL-37 is the only human cathelicidin antimicrobial peptide, a 37-amino acid cationic peptide derived from hCAP18 that exhibits broad-spectrum antimicrobial activity against bacteria, viruses, and fungi while modulating immune responses.

Primary Uses
Wound healing
Chronic Venous Leg Ulcers
Diabetic Foot Ulcers
Pressure Ulcers
Innate Immune Enhancement
Antimicrobial Resistance
Immunomodulation
Epithelial Cell Proliferation
Angiogenesis Promotion
Collagen Synthesis
Protocol Reference
Dose
0.5-1.6 mg/mL topical gel or 100-150 mcg injectable
Frequency
Topical: Daily to twice weekly on wounds. Injectable: Once daily subcutaneous
Half-life
Short (rapid proteolytic degradation)
Route
topical · subcutaneous injection
Evidence
Well Studied
Research Models
Human
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