Catalog4 refs
Thymulin
Immune ModulationResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
neural tissue
Overview
Thymulin is a nonapeptide hormone exclusively secreted by thymic epithelial cells, discovered by Jean-François Bach in the 1970s. Unlike thymalin (a peptide extract mixture), thymulin is a single, defined 9-amino-acid peptide that requires zinc binding for biological activity. It plays a crucial role in T-cell differentiation and maturation within the thymus. Serum thymulin levels decline significantly with age and zinc deficiency, contributing to age-related immune decline (immunosenescence). Research has explored thymulin's potential in restoring immune function, managing autoimmune conditions, and as an anti-inflammatory agent.
Primary Uses
Immunosenescence
T-Cell Deficiency
Zinc Deficiency States
Anti-Inflammatory Effects
Autoimmune Conditions
Type 1 Diabetes Research
HPA Axis Modulation
Neuroprotection
Protocol Reference
Dose
1-10mcg per injection
Frequency
Daily
Half-life
~10 minutes (free form); extended with nanoparticle formulations
Route
Subcutaneous · Intraperitoneal · Intranasal
Evidence
Well Studied
Also in Immune Modulation