Catalog4 refs
Thymulin (Facteur Thymique Sérique)
Immune ModulationResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
neural tissue
Overview
A zinc-dependent nonapeptide hormone exclusively secreted by thymic epithelial cells, discovered by Jean-François Bach in the 1970s. It requires zinc binding for biological activity and plays a crucial role in T-cell differentiation and maturation within the thymus. Serum thymulin levels decline significantly with age and zinc deficiency, contributing to age-related immune decline (immunosenescence).
Primary Uses
T-cell differentiation and maturation
Immunosenescence restoration
Anti-inflammatory effects
Autoimmune condition research
Type 1 Diabetes research
HPA axis modulation
Neuroprotection
Zinc deficiency states
Protocol Reference
Dose
1-10 mcg per injection
Frequency
Daily
Half-life
~10 minutes (free form); extended with nanoparticle formulations
Route
Subcutaneous · Intraperitoneal · Intranasal
Evidence
Well Studied
Also in Immune Modulation