Cerebrolysin
BioregulatorsCognition, Mood & NeuroprotectionnootropicNeurological RecoveryNootropic & NeuroCognitiveResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
Overview
A porcine brain-derived peptide preparation consisting of low-molecular-weight peptides and free amino acids obtained by enzymatic hydrolysis of purified pig brain proteins. Approved in over 50 countries for the treatment of stroke, traumatic brain injury (TBI), and dementia, though not FDA-approved. Mimics the action of endogenous neurotrophic factors (BDNF, NGF, CNTF), promoting neuronal survival, synaptic plasticity, and neurogenesis. Developed by EVER Neuro Pharma (Austria) and in clinical use since the 1970s.
Primary Uses
Stroke recovery
Traumatic brain injury (TBI) recovery
Dementia
Neuroprotection
Cognitive enhancement
Motor and cognitive recovery after stroke
Alzheimer's disease (preclinical)
Acute stroke recovery
Traumatic brain injury (TBI)
Vascular dementia
Cognitive decline
Stroke and TBI recovery research
Cognitive impairment models
Neurotrophic signaling
Neuroplasticity studies
Vascular dementia research
Acute ischaemic stroke recovery
Post-stroke depression
Aphasia after ischemic stroke
Alzheimer's Disease
Post-Stroke Cognitive Recovery
Acute Stroke
Traumatic Brain Injury
Subarachnoid Hemorrhage
Motor Function Recovery
Neurological Function
stroke research
traumatic brain injury (TBI) research
neurodegenerative disease research
Neuroprotection after brain trauma
Protocol Reference
Dose
10–50 mL
Frequency
Once Daily (acute) Or 5 Days Weekly (chronic)
Half-life
Complex mixture; single half-life not well defined
Route
Intramuscular
Evidence
Phase 4 / Large randomized controlled trials; approved in over 50 countries / Multiple Cochrane systematic reviews and meta-analyses / Well Studied / Research use only / Mixed - Cochrane reviews found insufficient/inconclusive evidence with high risk of bias; Alzheimer's Drug Discovery Foundation rates human evidence as mixed and far from conclusive (disputed)
Research References· 19
Research Models
HumanPorcine
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