Catalog3 refs
Chonluten
BioregulatorsRussian bioregulatory peptideResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
Overview
A Khavinson bioregulator tripeptide (EDG) derived from respiratory lung tissue, developed at Russia's St. Petersburg Institute of Bioregulation and Gerontology. It targets the bronchopulmonary system with secondary activity in the GI tract. Works through epigenetic regulation, penetrating cell and nuclear membranes to bind promoter or suppressor regions of DNA and modulate transcriptional control. Regulates genes including c-Fos, HSP70, SOD, COX-2, and TNF-alpha related to oxidative stress and proliferative regulation. Inhibits TNF production in monocytes exposed to pro-inflammatory LPS.
Primary Uses
Respiratory-system support
Inflammation and oxidative-stress studies
Lung tissue repair
Mucosal resilience
Normalizes respiratory system function
Regulates protein synthesis in lung tissue
Inhibits inflammatory TNF production
Restores lung alveolar tissues
Maintains bronchial mucous membranes
Supports antioxidant gene expression
Geroprotective anti-aging support
COPD support
Modulates mucosal function
Lung tissue support
Pulmonary research
respiratory support
chronic bronchitis with an asthmatic component
chronic obstructive pulmonary disease
age-related lung decline
Protocol Reference
Dose
10–20 mg
Frequency
1-2 times daily with food
Half-life
Not Well Characterized
Route
Oral
Evidence
Preclinical / Moderate Research (disputed)
Research References· 4
https://pubmed.ncbi.nlm.nih.gov/11713572/
PubMedPMID 11713572- [https://www.mdpi.com/1420-3049/26/22/7053](https://www.mdpi.com/1420-3049/26/22/7053)
Research Models
Humananimals
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