Catalog4 refs
Cyclic Glycine-Proline (cGP)
Nootropic & NeuroResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
Circulationneural stem cells
Overview
Endogenous cyclic dipeptide found in plasma, breast milk, and cerebrospinal fluid. Functions as metabolite of IGF-1, regulating its bioavailability through competitive binding to IGFBP-3. Demonstrates neuroprotective, cognitive-enhancing, and cardioprotective properties supported by clinical trials.
Primary Uses
Cognitive enhancement
Neuroprotection
Alzheimer's disease
Parkinson's disease
Type-2 diabetes
Blood pressure regulation
Stroke recovery
Healthy aging
IGF-1 optimization
Cardiovascular support
Metabolic health improvement
Protocol Reference
Dose
20-100 μg daily (or 300 mg blackcurrant extract 2x daily)
Frequency
Once daily, preferably in the morning
Half-life
Extended stability (more stable than linear GPE precursor)
Route
Oral capsule
Evidence
Moderate Research
Research Models
HumanMouse
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