Catalog4 refs
DNSP-11
Nootropic & NeuroResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
Mitochondria
Overview
DNSP-11 is an 11-amino acid peptide derived from the pro-domain of glial cell line-derived neurotrophic factor (GDNF). It was designed to capture the neuroprotective properties of GDNF while avoiding the limitations of the full-length protein, including poor blood-brain barrier penetration, off-target effects, and manufacturing complexity. Preclinical research demonstrates that DNSP-11 protects and stimulates dopaminergic neurons, making it a compound of significant interest for Parkinson's disease research and biohacking communities focused on dopamine system health.
Primary Uses
Protects dopaminergic neurons from neurotoxic insults
Stimulates dopamine production via tyrosine hydroxylase upregulation
Neuroprotection in Parkinson's disease models
Improves baseline motivation and drive
Improves mood stability and emotional baseline
Supports mitochondrial function in dopaminergic neurons
Protocol Reference
Dose
100-200mcg per day
Frequency
1x daily (morning recommended)
Half-life
Not well characterized
Route
Intranasal · Subcutaneous
Evidence
Limited Research
Also in Nootropic & Neuro