Catalog11 refs
IGF-1 LR3
Healing & RecoveryMuscle & PerformancetherapeuticResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
MusclesJointsSkin
Overview
IGF-1 LR3 (Long R3 IGF-1) is a modified form of insulin-like growth factor 1 with significantly enhanced potency and half-life compared to native IGF-1. The modifications — an arginine substitution at position 3 and a 13-amino-acid N-terminal extension — reduce binding to IGF binding proteins (IGFBPs) by approximately 100-fold, leaving dramatically more free IGF-1 available to activate IGF-1 receptors. With a half-life extended from minutes to approximately 20–30 hours, IGF-1 LR3 is one of the most potent anabolic peptides researched for muscle growth, cell proliferation, and tissue repair.
Primary Uses
Muscle growth / anabolic
Cell proliferation / recovery
Metabolic
muscle growth
cell proliferation
tissue repair
cell culture media supplement
Cell growth and hypertrophy models
Reduced IGFBP-binding studies
Muscle anabolism
Recovery protocols
Muscle hypertrophy
Anti-catabolism
Muscle hyperplasia
Wound healing
Ligament/tendon recovery
Nutrient partitioning
Fat loss
Protocol Reference
Dose
20–100mcg (start low
Frequency
Injection (subcutaneous)
Half-life
4-6 weeks maximum; equal break recommended
Route
escalate based on response)
Evidence
limited / Preclinical (disputed)
Research References· 5
Research Models
MouseRatSheep
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