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Normoftal

BioregulatorsCognitiveResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Not Well Characterized
Half-life
13
Uses
100
Typical
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Overview

Khavinson retinal bioregulator containing short peptides (reportedly lysine and glutamic acid, marketed as 'AKS-G') intended to support retinal cells. Proposed mechanism involves correcting age- or disease-related 'peptide deficiency' and restoring normal cellular function in the retina via tissue-specific gene expression signaling. Approved in Russia as a dietary supplement for retinal support; not FDA-approved. Evidence is concentrated within Khavinson's own research institute with limited independent replication.

Primary Uses
Retinal support research
Glaucoma/cataract adjunct models
Eye tissue metabolism
Vision aging studies
Diabetic retinopathy research
Retinal degeneration
Glaucoma
Cataracts
Diabetic retinopathy
Post-surgical recovery
Macular degeneration
Retinitis pigmentosa
Prevention of age-related eye conditions
Protocol Reference
Dose
100–200 mcg
Frequency
Daily
Half-life
Not Well Characterized
Route
Oral
Evidence
Low — evidence concentrated within Khavinson's institute; not replicated by independent international groups to modern standards (disputed)
Research References· 3
Transport of Biologically Active Ultrashort Peptides Using POT and LAT Carriers.↗
Europe PMCPMID 35887081Int J Mol Sci2022
One-Step Synthesis of Normoftal↗
DOIPharmaceutical Chemistry Journal2014Balaev A, Reshetnikov E, Fedorov V
APPLICATION OF NORMOFTAL IN PATIENTS WITH DIABETIC RETINOPATHY↗
DOIProblems of Endocrine Pathology2011Soboleva I
Research Models
Human
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