Catalog4 refs
P21 (P021)
Nootropic & NeuroResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
Overview
A nootropic peptide derived from ciliary neurotrophic factor (CNTF) that enhances neurogenesis and cognitive function. Contains an adamantane moiety enabling blood-brain barrier penetration. Increases BDNF expression, inhibits LIF signaling to promote neurogenesis, and reduces tau and amyloid pathology in Alzheimer's disease models. Can boost neurogenesis in diseased brains above levels seen in healthy untreated brains.
Primary Uses
Alzheimer's Disease treatment
Neurodegeneration prevention
Tau pathology reduction
Amyloid-beta plaque reduction
Neurogenesis enhancement
Memory enhancement
Age-related cognitive decline reduction
Synaptic plasticity restoration
Neuronal plasticity restoration
Cognitive function improvement
Protocol Reference
Dose
Variable by study - dosing not established for humans
Frequency
Daily
Half-life
Over 3 hours (mouse plasma)
Route
Subcutaneous · Intraperitoneal
Evidence
Emerging
Research Models
Mouse
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