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PEG-MGF (Pegylated MGF)

Healing & RecoveryResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
48-72 hours
Half-life
9
Uses
200-400mcg per
Typical
Body Map
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MusclesJoints
Overview

Pegylated Mechano Growth Factor, an IGF-1Ec splice variant C-terminal peptide with PEG attachment extending half-life from minutes to 48-72 hours. Activates muscle satellite stem cells via receptor binding, stimulating MAPK/ERK signaling. Enhances protein synthesis and promotes muscle fiber repair. E-peptide domain exhibits distinct activity from mature IGF-1.

Primary Uses
Muscle repair via satellite cell activation
Delayed senescence in muscle progenitor cells
Enhanced satellite cell fusion potential
Tendon healing
Bone regeneration
Cartilage repair
Exercise recovery
Injury recovery
Neuroprotection against oxidative stress
Protocol Reference
Dose
200-400mcg per injection (conservative: 100-200mcg)
Frequency
2-3x weekly, ideally post-workout
Half-life
48-72 hours
Route
Subcutaneous · Intramuscular
Evidence
limited
Research Models
HumanRabbitanimal
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