Catalog4 refs
TB-500 (Ac-LKKTETQ)
Healing & RecoveryResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
MusclesSkinCirculationJointstissues
Overview
TB-500 (Ac-LKKTETQ) is a synthetic derivative of thymosin beta-4 consisting of the N-terminal acetylated 17-23 amino acid fragment. This sequence represents the active site within thymosin beta-4 responsible for actin binding, cell migration, and wound healing. Research shows it promotes endothelial cell differentiation, angiogenesis, keratinocyte migration, collagen deposition, and decreases inflammation. The acetylation protects against N-terminal degradation while maintaining biological activity.
Primary Uses
Promotes wound healing
Enhances cell migration
Supports angiogenesis (new blood vessel formation)
Reduces inflammation
Promotes keratinocyte migration
Supports collagen deposition
Enhances tissue repair
Tissue regeneration
Protocol Reference
Dose
2-2.5 mg per injection (loading phase); 2 mg (maintenance)
Frequency
2x weekly (loading phase); weekly or bi-weekly (maintenance)
Half-life
Not precisely established; effects persist longer than 24 hours
Route
Subcutaneous injection
Evidence
Moderate Research
Research Models
Human
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