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TB-500 (Thymosin Beta-4 Fragment)

Healing & RecoveryInjury, Repair & RecoveryTissue RepairResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
~2 hours
Half-life
17
Uses
2-5mg per
Typical
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Overview

A synthetic 7-amino acid fragment corresponding to the actin-binding region of thymosin beta-4, originally developed for equine use with retained tissue repair properties. TB-500 acts as principal actin-sequestering protein, regulating cell migration, promoting angiogenesis, reducing inflammation, and activating stem cell differentiation.

Primary Uses
Wound healing
Tissue regeneration
Reducing inflammation
Promoting cell migration to injury sites
Stimulating new blood vessel formation (angiogenesis)
Enhancing capillary tube formation and vascular network development
Reducing inflammatory cytokine release
Inhibiting NF-κB signaling
Modulating extracellular matrix remodeling and collagen deposition
Muscle Regeneration
Tendon & Ligament Healing
Exercise Recovery
Injury Prevention
Performance Enhancement
Neuroprotection
Spinal Cord Injury Support
Brain Health
Protocol Reference
Dose
2-5mg per injection (higher doses for serious injuries)
Frequency
2-3x weekly
Half-life
~2 hours
Route
Subcutaneous · Intramuscular · Topical
Evidence
Well Studied / Phase 2 (disputed)
Research Models
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