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Thymogen

BioregulatorsThymus Immune BioregulatorImmuneResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Short (dipeptide)
Half-life
25
Uses
50
Typical
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Overview

Thymogen (EW dipeptide) is a Khavinson bioregulator consisting of glutamic acid and tryptophan, originally isolated from calf thymus extracts (Thymalin) in the late 1980s. Developed by Professor Vladimir Khavinson, it has been registered in Russia since 1990 in multiple forms including injectable solution, nasal spray, and topical cream. Thymogen modulates both humoral and cellular immunity, activates T-cell differentiation, and has demonstrated geroprotective (anti-aging) and antitumor activities in research studies.

Primary Uses
Immune modulation
T-cell function support
Mucosal immunity studies
Recovery protocols
Hepatoprotective effects
Hypolipidemic activity
Treatment of type-1 diabetes mellitus
Radiation-induced carcinogenesis modulation
Dentinogenesis stimulation
Psychotropic effects
Immune System Modulation
T-Cell Function
Immunoglobulin Production
Post-Operative Recovery
Geroprotection
Lifespan Extension
Antitumor Activity
Cancer Support
Heart Disease
Diabetes Support
Immunomodulation
T-cell differentiation
Neutrophil chemotaxis and phagocytosis enhancement
Anti-tumor effects (animal studies)
Immune support in immunocompromised states
Protocol Reference
Dose
50–100 mcg
Frequency
2 Times A Day Intranasal/1 Time Daily Injection
Half-life
Short (dipeptide)
Route
Intranasal · Intramuscular
Evidence
Russian clinical research / Khavinson Institute / Well Studied / Preclinical (disputed)
Research References· 14
Russian Clinical Practice \- Over 20 years of clinical immunomodulation use ↗
PubMedPMID 14523363100 mcg intranasal
The use of thymogen to stimulate the sexual function of cows↗
DOIVeterinaria i kormlenie2025Khristianovsky P, Medetov E, Aldyarov T, et al.
Hepatoprotective Effects of Thymogen Analogues in Hydrazine Hepatopathy in Rats.↗
PubMedPMID 40442470Bull Exp Biol Med2025Chulanova AA, Smakhtina AM, Mal GS, Bobyntsev II, et al.
Research Models
BovineHumanMouseRat
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