Veslugen

Veslugen is the vendor spelling for Vesugen, a synthetic tripeptide with the sequence Lys-Glu-Asp (KED) from Vladimir Khavinson's Russian bioregulator program, studied as a vascular bioregulator. It is a single defined molecule (formula C15H26N4O8, around 390 Da). The core hypothesis is that this very short peptide can enter cells, reach the nucleus, and bind directly to specific DNA sequences in gene promoters, acting as an epigenetic switch that tunes the activity of vascular genes. Molecular docking and cell work suggest KED may bind near the MKI67 (Ki-67) promoter and may influence endothelial genes such as endothelin-1, connexins, and sirtuin-1, helping endothelial cells maintain or restore normal function with age.