Catalog9 refs
Vesugen
BioregulatorsLongevity & MitochondrialCardiovascularResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
Circulationstem cells
Overview
Vesugen is a Khavinson bioregulator tripeptide composed of lysine, glutamic acid, and aspartic acid (KED) that targets the vascular system and protects blood vessels from age-related decline. It works through epigenetic regulation by interacting with DNA promoter regions, affecting Ki-67 gene expression and regulating SIRT1 protein levels. It enhances mesenchymal stem cell proliferation, reduces senescence markers, and may reverse the Senescence-Associated Secretory Phenotype (SASP).
Primary Uses
Vascular/endothelial support
Microcirculation studies
Cardiovascular aging
Blood-vessel resilience
Protects vascular system from aging effects
Limits atherosclerosis development
Decreases endothelial cell dysfunction
Activates SIRT1 anti-aging pathway
Enhances stem cell proliferation
Reduces cellular senescence markers
Reverses SASP phenotype
Vascular system research
Vascular system support
Vascular support
Neuroprotective effects
Cardiovascular support
Restoration of dendritic spine density in Alzheimer's models
Protocol Reference
Dose
20–40 mg
Frequency
1-2 times daily before food
Half-life
Short (tripeptide)
Route
Oral
Evidence
Preclinical / Moderate Research (disputed)
Research Models
HumanMouse
Also in Bioregulators