Catalog3 refs
Vesugen (KED)
BioregulatorsResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
Circulationstem cells
Overview
Vesugen is a Khavinson bioregulator tripeptide composed of lysine, glutamic acid, and aspartic acid (KED) that targets the vascular system and protects blood vessels from age-related decline. It works through epigenetic regulation by interacting with DNA promoter regions, particularly affecting Ki-67 gene expression and regulating SIRT1 protein levels. It enhances mesenchymal stem cell proliferation, reduces senescence markers, and may reverse the Senescence-Associated Secretory Phenotype (SASP).
Primary Uses
Protects vascular system from aging effects
Limits atherosclerosis development
Decreases endothelial cell dysfunction
Activates SIRT1 anti-aging pathway
Enhances stem cell proliferation
Reduces cellular senescence markers
Reverses SASP phenotype
Cellular rejuvenation
Protocol Reference
Dose
10-20 mg per day (oral capsules) or 10 mg (injectable)
Frequency
Daily for 10-20 consecutive days; 2-3 cycles yearly for maintenance
Half-life
Not established
Route
Oral capsules · Injectable
Evidence
Moderate Research
Research Models
Human
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