Catalog179 refs
ACTH (Cosyntropin)
OtherResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
Overview
Cosyntropin is a synthetic version of the first 24 building blocks of the body's natural stress hormone ACTH. It binds MC2R receptors on adrenal cortex cells to stimulate cortisol and corticosteroid synthesis, used diagnostically to assess adrenal reserve and therapeutically for specific conditions like infantile spasms.
Primary Uses
Diagnostic tool to test adrenal gland function
Assess adrenal reserve
Treat infantile spasms
Treat nephrotic syndrome
Protocol Reference
Dose
250 mcg (standard) or 1 mcg (low-dose test)
Frequency
Single dose (diagnostic) or per protocol (therapeutic)
Route
Intravenous (IV) · Intramuscular (IM)
Evidence
Phase 4
Research Models
Human
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