Adrenocorticotropic hormone (ACTH)
OtherResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
Muscles
Overview
ACTH binds to MC2R on adrenal cortex cells, activating cAMP/PKA pathway to stimulate cortisol synthesis and release. Chronic ACTH stimulation promotes adrenal cortex hypertrophy and hyperplasia.
Primary Uses
adrenal insufficiency diagnosis
adrenal insufficiency treatment
muscle growth