Catalog11 refs
Calcitonin
MetabolicMusculoskeletalHormonalResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
Circulation
Overview
Calcitonin is a 32-amino-acid peptide hormone made by the parafollicular (C) cells of the thyroid gland, and it lowers blood calcium by putting the brakes on bone breakdown. The therapeutic version is usually salmon calcitonin, which is more potent and longer-lasting than the human form, sold as Miacalcin and similar products in injectable and nasal-spray forms. It is FDA-approved for Paget's disease of bone, hypercalcemia, and postmenopausal osteoporosis, though its osteoporosis role has shrunk dramatically over the years.
Primary Uses
Bone turnover studies
Calcium homeostasis
Analgesia in vertebral-fracture models
Osteoclast inhibition
hypercalcemia
osteoporosis treatment
bone resorption inhibition
increased calcium excretion
Osteoporosis
Paget's disease
Acute vertebral fracture pain
Protocol Reference
Dose
~100 mcg daily
Frequency
Daily
Half-life
Approximately 10-60 minutes depending on route/formulation
Route
Intranasal · Subcutaneous
Evidence
FDA Approved / FDA approved formulations available (disputed)
Research References· 18
Calcitonin↗
DOISpringerReference
Research Models
HumanSalmon
Also in Metabolic