Catalog11 refs
GHRP-6
Growth Hormone SecretagogueGrowth Hormone / IGF-1 AxistherapeuticGrowth HormoneResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
Muscles
Overview
GHRP-6 (Growth Hormone Releasing Peptide 6) is a synthetic hexapeptide that stimulates growth hormone release through ghrelin receptor (GHSR-1a) activation. It is notable for producing strong GH release alongside the most intense appetite stimulation of any GHRP — making hunger its defining characteristic. First synthesized in the 1980s by Cyril Bowers at Tulane University, GHRP-6 was instrumental in the discovery of the ghrelin receptor (GHSR-1a) and the subsequent identification of ghrelin itself by Kojima et al. in 1999. Beyond GH release, GHRP-6 has demonstrated cytoprotective properties in cardiac and hepatic tissue through GH-independent mechanisms.
Primary Uses
Triggers growth hormone release
Stimulates appetite
Synergizes with GHRH analogs for greater GH release
muscle growth
anti aging
appetite stimulation
cardiac ischemia-reperfusion injury reduction
hepatoprotection
GH release and appetite studies
Ghrelin signaling research
Recovery protocols
Body-composition research
Diagnosis of GH deficiency
Acute kidney injury therapy via metabolic regulation
Prevention of doxorubicin-induced myocardial and extra-myocardial damage
Pro-autophagic effects on skeletal muscle
Potent stimulation of natural growth hormone release
Significant increase in appetite (beneficial for bulking/weight gain)
Enhanced muscle growth through elevated GH and IGF-1
Improved fat metabolism and body composition
Cardioprotective effects observed in research
Enhanced recovery from exercise and injury
Cytoprotective and anti-inflammatory properties
Maintains natural GH pulsatile release
Indirectly increases IGF-1 levels through enhanced GH secretion from the pituitary
Faster recovery from exercise and improved tissue repair
Antioxidant effects - attenuation of reactive oxygen species and preservation of antioxidant defenses
Fat loss
Growth hormone release
Increased appetite
Lab and diagnostic probe
Protocol Reference
Dose
100–300mcg per injection
Frequency
2-3 times daily
Half-life
~2 Hours
Route
Injection
Evidence
Phase 2 / Well Studied / B / Preclinical/Investigational (disputed)
Research References· 21
Research Models
HumanMouseanimals
Also in Growth Hormone Secretagogue