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Glucagon

MetabolicHormonalResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Half-life
5
Uses
1 mg
Typical
Body Map
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Overview

Glucagon is insulin's counterweight, a 29-amino-acid peptide hormone secreted by the alpha cells of the pancreas that raises blood sugar instead of lowering it. When glucose drops, glucagon tells the liver to break down stored glycogen and make new glucose, pushing blood sugar back up. Medically it is the emergency rescue treatment for severe hypoglycemia, available as injectable kits and a nasal-spray form, and it is also used in some diagnostic imaging to relax the gut.

Primary Uses
Treatment of severe hypoglycemia
Diagnostic procedures
Emergency rescue treatment for severe hypoglycemia
Diagnostic imaging to relax the gut
Target in next-generation metabolic drug research for obesity and diabetes
Protocol Reference
Dose
1 mg IM/SC/IV for hypoglycemia; 3 mg intranasal (Baqsimi)
Frequency
Single dose emergency use
Route
Injection · intranasal · auto-injector
Evidence
FDA Approved / FDA approved (disputed)
Research References· 1
FDA Approved Labeling \- Prescribed dose ↗
PubMedPMID 303559953 mg intranasal (Baqsimi)
Research Models
HumanMouse
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