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Pemvidutide

MetabolicResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Half-life
5
Uses
Typical
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Overview

Pemvidutide (also known as ALT-801) is a dual GLP-1/glucagon receptor agonist peptide that binds to both GLP-1 and glucagon receptors, activating Gs proteins to increase cAMP. This stimulates insulin secretion, reduces appetite, delays gastric emptying, and increases energy expenditure. It is being investigated for MASH, obesity, and ALD and is not yet FDA-approved.

Primary Uses
Weight loss
MASH improvement
Increased energy expenditure
Reduced appetite
ALD treatment (theoretical)
Protocol Reference
Evidence
Clinical trials ongoing
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