Catalog5 refs
THR-123
MetabolicResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
Overview
THR-123 is a small synthetic 16-residue cyclic peptide designed to mimic part of the protein BMP7 (bone morphogenetic protein 7) and switch on its receptor, ALK3, in the kidney. It is a preclinical research compound with no human trials of its own, though its intravenous sibling THR-184 reached Phase 2 for acute kidney injury.
Primary Uses
Reversal of established kidney fibrosis
Kidney regeneration
Pancreatic beta-cell regeneration
Protocol Reference
Dose
2-10 mg per day, oral (community extrapolated from animal data)
Frequency
Once daily
Route
Oral · Intraperitoneal injection
Evidence
Preclinical
Research References· 1
Research Models
HumanMouse
Also in Metabolic