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Copper Peptide AHK-Cu

Cosmetic & DermalResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Half-life
7
Uses
Limited community
Typical
Body Map
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SkinCirculation
Overview

AHK-Cu is a synthetic copper-bound tripeptide (alanine-histidine-lysine complexed with a copper ion), engineered mainly for hair and scalp products. It is the lesser-known sibling of the naturally occurring GHK-Cu copper peptide, designed to push hair follicles to keep growing. It acts as a carrier and signal for copper, involved in tissue repair, blood vessel growth and collagen remodeling. In hair, the proposed action centers on dermal papilla cells, keeping them alive and dividing longer by shifting the balance of survival proteins (more Bcl-2, less Bax) to reduce programmed cell death and extend the active growth phase.

Primary Uses
Hair growth stimulation
Scalp care
Dermal papilla cell proliferation
Reducing follicle apoptosis
Tissue repair
Blood vessel growth
Collagen remodeling
Protocol Reference
Dose
Limited community data available; see research protocols
Frequency
Applied to scalp daily
Route
Topical (scalp serums, solutions)
Evidence
Preclinical
Research References· 2
Research Literature \- Observed in studies ↗
PubMedPMID 17763607Applied to scalp daily
https://pubmed.ncbi.nlm.nih.gov/17703734/
PubMedPMID 17703734- [https://link.springer.com/article/10.1007/BF02978833](https://link.springer.com/article/10.1007/BF02978833)
Research Models
Human
Also in Cosmetic & Dermal
Cosmetic & Dermal
AHK-Cu
Stimulates hair follicle growth · Extends anagen (active growth) phase of hair cycle
Cosmetic & Dermal
Argireline
Wrinkle reduction · Softening expression lines
Cosmetic & Dermal
Argireline (Acetyl Hexapeptide-3)
Wrinkle reduction · Softening expression lines around eyes and forehead
Cosmetic & Dermal
GHK-Cu
Wound healing · Skin regeneration
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