Enkephalins (Met-enkephalin, Leu-enkephalin)
OtherResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
Overview
Endogenous opioid neurotransmitters - rapidly degraded by peptidases. Enkephalins bind to delta and mu opioid receptors, activating Gi/o proteins to inhibit adenylate cyclase and reduce neurotransmitter release, particularly in pain pathways.
Primary Uses
Analgesia
Stress Response Modulation
Mood Modulation
Protocol Reference
Half-life
Rapidly degraded by enkephalinases (neprilysin, aminopeptidase N)
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