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Gonadorelin (GnRH)

OtherResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Half-life
6
Uses
50
Typical
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Overview

Gonadorelin is a synthetic form of gonadotropin-releasing hormone (GnRH), a key reproductive signaling hormone. It mimics endogenous GnRH signaling to stimulate pulsatile release of LH and FSH, maintaining gonadal function and fertility. It is used diagnostically and therapeutically for fertility assessment, low hormone levels, and to maintain testicular function during testosterone replacement therapy.

Primary Uses
Fertility assessment
Treatment of low hormone levels
Maintaining testicular function during TRT
Stimulating ovulation in women
Stimulating spermatogenesis in men with hypothalamic hypogonadism
Preserving fertility and testicular size during TRT
Protocol Reference
Dose
50–100 mcg
Frequency
2–3× daily or pulsatile pump
Route
Subcutaneous (SC) · Intramuscular (IM)
Evidence
Phase 4, FDA Approved
Research Models
Human
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