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Matrixyl

Cosmetic & DermalSkin & HairResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Half-life
13
Uses
3-8% in
Typical
Body Map
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Skin
Overview

A fat-soluble signal peptide used in cosmetic skincare to boost collagen production. It mimics collagen breakdown fragments (matrikines) to signal fibroblasts to increase collagen synthesis, promoting skin repair and reducing wrinkle depth. It is one of the most clinically validated anti-wrinkle peptides and is found primarily in topical products.

Primary Uses
Boost collagen production
Reduce wrinkle depth
Promote skin repair
Improve skin hydration
Increase extracellular matrix density
Collagen synthesis stimulation
Tissue repair
Reducing wrinkle depth
Improving skin elasticity
Fine lines reduction
Skin firmness
Skin texture improvement
Collagen synthesis
Protocol Reference
Dose
3-8% in formulations
Frequency
Applied twice daily
Route
Topical (serums, creams)
Evidence
Cosmetic use - Extensively studied / Preclinical / Limited (disputed)
Research Models
Human
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