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OS-01

OtherResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Half-life
4
Uses
Applied topically
Typical
Body Map
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Skin
Overview

OS-01 is a proprietary peptide developed by OneSkin Technologies, marketed as the first topical senolytic peptide for skin. It is designed to selectively reduce senescent cells in skin tissue — aged, dysfunctional cells that accumulate with age and secrete inflammatory factors (the senescence-associated secretory phenotype, or SASP) that damage surrounding tissue. OS-01 is the active ingredient in OneSkin's topical skincare products.

Primary Uses
Reduction of senescent cells in skin tissue
Reduction of SASP inflammatory factors
Epigenetic age reversal in skin
Improved skin barrier function and hydration
Protocol Reference
Dose
Applied topically twice daily to clean skin. Peptide concentration in commercial products is proprietary. Not available as a standalone research peptide — sold only as part of finished cosmetic products.
Frequency
Twice daily
Route
topical
Research References· 1
Senotherapeutic peptide treatment reduces biological age and senescence in human skin models
PubMedPMID 37460553. npj Aging, 2023.
Research Models
Human
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