Catalog4 refs
Snap-8
Cosmetic & DermalCosmetic & DermatologicalSkin & HairResearch use only
Educational use only. Not medical advice. Verify all information with primary sources and a licensed clinician before use.
Body Map
SkinMusclesnerves
Overview
SNAP-8 (Acetyl Octapeptide-3) is a synthetic eight-amino-acid topical cosmetic peptide, an extended cousin of Argireline that adds two residues to the same SNAP-25 mimic sequence. It is marketed as a needle-free way to soften expression lines, especially on the forehead and around the eyes. It is a cosmetic ingredient, not an approved drug, and the human evidence behind it is thin and mostly comes from the manufacturer. The proposed mechanism is that SNAP-8 imitates the tip of SNAP-25, competing for a spot in the SNARE complex to dial down muscle firing and reduce creasing, a gentler, reversible echo of how Botox works.
Primary Uses
Wrinkle Reduction
Softening expression lines
Reducing wrinkle depth
Anti-aging skincare
Botox-mimic topical alternative
Protocol Reference
Dose
3-10% in topical formulations
Frequency
Twice daily
Route
Topical (serums, creams)
Evidence
Preclinical
Research References· 1
Research Models
Human
Also in Cosmetic & Dermal